Each version of a modern OS has its own set of backward compatibility problems, and no exception to this is Windows 10.
The shift from Windows 8.1 to 10 is much less disturbing than the shift from Windows 7 to 8 was, but there are still some programs that can get disabled and stop running at all in some instances.
Try searching for an update in the Windows Store if a program is not running with Windows 10 and, if that doesn't work, delete and reinstall it.
The majority of programs should be compatible with the operating system now that Windows 10 has been out for just several years. If they are not, then they're probably never going to be.
Consider upgrading to a newer version of the software, or it could be time to pursue alternatives if it has stopped being created.